/* AIE™ v1.0.0 — Phase-Specific Stylesheet */

/* Phase Container */
#phase-container {
    animation: fadeIn 0.2s ease-in;
}

@keyframes fadeIn {
    from { opacity: 0; }
    to { opacity: 1; }
}

/* Phase Title */
.phase-title {
    font-size: 28px;
    font-weight: 700;
    color: var(--color-primary);
    margin-bottom: var(--spacing-md);
}

.phase-description {
    font-size: var(--font-size-base);
    color: var(--color-text-secondary);
    margin-bottom: var(--spacing-xl);
    line-height: 1.6;
}

/* Phase 0: Patient Entry */
.patient-data-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: var(--spacing-lg);
}

.data-section {
    background-color: white;
    border: var(--border-width) solid var(--color-border);
    border-radius: var(--border-radius);
    padding: var(--spacing-lg);
}

.data-section-title {
    font-size: var(--font-size-large);
    font-weight: 600;
    margin-bottom: var(--spacing-md);
    color: var(--color-primary);
    border-bottom: 2px solid var(--color-primary);
    padding-bottom: var(--spacing-sm);
}

.form-row {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: var(--spacing-md);
}

.checkbox-group {
    display: flex;
    align-items: center;
    gap: var(--spacing-sm);
    margin-bottom: var(--spacing-md);
}

.checkbox-group input[type="checkbox"] {
    width: 20px;
    height: 20px;
    cursor: pointer;
}

.checkbox-group label {
    cursor: pointer;
    user-select: none;
}

/* Calculated Fields Display */
.calculated-field {
    padding: var(--spacing-md);
    background-color: #e3f2fd;
    border-left: 4px solid var(--color-info);
    border-radius: var(--border-radius);
    margin-top: var(--spacing-sm);
}

.calculated-field-label {
    font-weight: 600;
    color: var(--color-info);
    margin-bottom: var(--spacing-xs);
}

.calculated-field-value {
    font-size: var(--font-size-large);
    font-weight: 700;
    color: var(--color-text);
}

/* Phase 1: Syndrome Classification */
.syndrome-grid {
    display: grid;
    grid-template-columns: repeat(auto-fill, minmax(280px, 1fr));
    gap: var(--spacing-md);
    margin-bottom: var(--spacing-xl);
}

.syndrome-card {
    background-color: white;
    border: 2px solid var(--color-border);
    border-radius: var(--border-radius);
    padding: var(--spacing-lg);
    cursor: pointer;
    transition: all 0.2s;
    position: relative;
}

.syndrome-card:hover {
    border-color: var(--color-primary);
    box-shadow: var(--shadow-md);
    transform: translateY(-2px);
}

.syndrome-card:focus-visible {
    outline: 3px solid var(--color-primary);
    outline-offset: 2px;
}

.syndrome-card.selected {
    border-color: var(--color-primary);
    background-color: #e3f2fd;
    box-shadow: var(--shadow-md);
}

.syndrome-code {
    display: inline-block;
    background-color: var(--color-primary);
    color: white;
    padding: var(--spacing-xs) var(--spacing-sm);
    border-radius: var(--border-radius);
    font-weight: 700;
    font-size: 14px;
    margin-bottom: var(--spacing-sm);
}

.syndrome-card.selected .syndrome-code {
    background-color: var(--color-success);
}

.syndrome-name {
    font-size: 18px;
    font-weight: 700;
    color: var(--color-text);
    margin-bottom: var(--spacing-sm);
}

.syndrome-definition {
    font-size: 14px;
    color: var(--color-text-secondary);
    line-height: 1.4;
    margin-bottom: var(--spacing-sm);
}

.syndrome-requirements {
    font-size: 13px;
    color: var(--color-text-secondary);
    font-style: italic;
    padding-top: var(--spacing-sm);
    border-top: var(--border-width) solid var(--color-border);
}

.syndrome-critical {
    background-color: #fff3e0;
    border-color: var(--color-warning);
    padding: var(--spacing-sm);
    border-radius: var(--border-radius);
    margin-top: var(--spacing-sm);
    font-size: 13px;
    font-weight: 600;
    color: var(--color-warning);
}

.syndrome-critical::before {
    content: '⚠️ ';
}

/* Selected Syndrome Display */
.selected-syndrome-display {
    background-color: #e8f5e9;
    border: 2px solid var(--color-success);
    border-radius: var(--border-radius);
    padding: var(--spacing-lg);
    margin-bottom: var(--spacing-xl);
}

.selected-syndrome-display .syndrome-code {
    background-color: var(--color-success);
}

.selected-syndrome-display .syndrome-name {
    font-size: 24px;
    color: var(--color-success);
}

/* Validation Summary */
.validation-summary {
    background-color: white;
    border: 2px solid var(--color-border);
    border-radius: var(--border-radius);
    padding: var(--spacing-lg);
    margin-bottom: var(--spacing-lg);
}

.validation-summary-title {
    font-size: var(--font-size-large);
    font-weight: 700;
    margin-bottom: var(--spacing-md);
    color: var(--color-text);
}

.validation-item {
    display: flex;
    align-items: flex-start;
    gap: var(--spacing-sm);
    padding: var(--spacing-sm) 0;
}

.validation-item::before {
    content: '✓';
    color: var(--color-success);
    font-weight: 700;
    font-size: 20px;
    flex-shrink: 0;
}

.validation-item.incomplete::before {
    content: '○';
    color: var(--color-text-secondary);
}

.validation-item.error::before {
    content: '✗';
    color: var(--color-danger);
}

/* Source Control Required Banner */
.source-control-banner {
    background-color: #fff3e0;
    border: 2px solid var(--color-warning);
    border-radius: var(--border-radius);
    padding: var(--spacing-md);
    margin-bottom: var(--spacing-lg);
    display: flex;
    align-items: center;
    gap: var(--spacing-md);
}

.source-control-banner::before {
    content: '⚠️';
    font-size: 32px;
    flex-shrink: 0;
}

.source-control-banner strong {
    color: var(--color-warning);
}

/* Navigation Buttons */
.phase-navigation {
    display: flex;
    justify-content: space-between;
    align-items: center;
    gap: var(--spacing-md);
    margin-top: var(--spacing-xl);
    padding-top: var(--spacing-xl);
    border-top: var(--border-width) solid var(--color-border);
    flex-wrap: wrap;
}

/* Save & Pause buttons - always visible and prominent */
.phase-navigation .btn-warning,
#pause-case-phase3,
#pause-case-phase4,
#pause-case-phase5,
#pause-case-phase6,
#pause-case-phase7 {
    background-color: #ff9800 !important;
    color: white !important;
    font-weight: 600 !important;
    min-width: 160px;
    flex-shrink: 0;
}

.phase-navigation .btn-back {
    background-color: transparent;
    color: var(--color-primary);
    border: 2px solid var(--color-primary);
}

.phase-navigation .btn-back:hover:not(:disabled) {
    background-color: var(--color-primary);
    color: white;
}

/* Radio Button Groups */
.radio-group {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-sm);
}

.radio-option {
    display: flex;
    align-items: center;
    gap: var(--spacing-sm);
    padding: var(--spacing-sm);
    border: var(--border-width) solid var(--color-border);
    border-radius: var(--border-radius);
    cursor: pointer;
    transition: all 0.2s;
}

.radio-option:hover {
    background-color: var(--color-surface);
}

.radio-option input[type="radio"] {
    width: 20px;
    height: 20px;
    cursor: pointer;
}

.radio-option label {
    cursor: pointer;
    flex: 1;
    user-select: none;
}

.radio-option.selected {
    background-color: #e3f2fd;
    border-color: var(--color-primary);
}

/* Data Review Section */
.data-review {
    background-color: white;
    border: var(--border-width) solid var(--color-border);
    border-radius: var(--border-radius);
    padding: var(--spacing-lg);
    margin-bottom: var(--spacing-lg);
}

.data-review-title {
    font-size: var(--font-size-large);
    font-weight: 700;
    margin-bottom: var(--spacing-md);
    color: var(--color-primary);
}

.data-review-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: var(--spacing-md);
}

.data-review-item {
    padding: var(--spacing-sm) 0;
    border-bottom: var(--border-width) solid var(--color-surface);
}

.data-review-label {
    font-size: 13px;
    font-weight: 600;
    color: var(--color-text-secondary);
    text-transform: uppercase;
    letter-spacing: 0.5px;
    margin-bottom: var(--spacing-xs);
}

.data-review-value {
    font-size: var(--font-size-base);
    font-weight: 600;
    color: var(--color-text);
}

.data-review-value.highlighted {
    color: var(--color-primary);
    font-weight: 700;
}

/* Loading State */
.loading-spinner {
    display: inline-block;
    width: 20px;
    height: 20px;
    border: 3px solid var(--color-surface);
    border-top-color: var(--color-primary);
    border-radius: 50%;
    animation: spin 0.8s linear infinite;
}

@keyframes spin {
    to { transform: rotate(360deg); }
}

/* Phase 2: Coverage Requirement Mapping */
.coverage-section {
    margin-bottom: var(--spacing-xl);
}

.coverage-section-title {
    font-size: 18px;
    font-weight: 700;
    color: var(--color-primary);
    margin-bottom: var(--spacing-md);
}

.coverage-list {
    list-style: none;
    padding: 0;
}

.coverage-item {
    padding: var(--spacing-md);
    margin-bottom: var(--spacing-sm);
    border: var(--border-width) solid var(--color-border);
    border-radius: var(--border-radius);
    background-color: white;
}

.coverage-badge {
    display: inline-block;
    padding: var(--spacing-xs) var(--spacing-sm);
    border-radius: var(--border-radius);
    font-size: 12px;
    font-weight: 700;
    text-transform: uppercase;
    margin-right: var(--spacing-sm);
}

.coverage-badge.mandatory {
    background-color: var(--color-danger);
    color: white;
}

.coverage-badge.conditional {
    background-color: var(--color-warning);
    color: white;
}

.coverage-badge.exclusion {
    background-color: var(--color-text-secondary);
    color: white;
}

.coverage-note {
    display: block;
    margin-top: var(--spacing-xs);
    font-size: 14px;
    color: var(--color-text-secondary);
    font-style: italic;
}

/* Phase 3: Regimen Selection */
.regimen-section {
    margin-bottom: var(--spacing-xl);
}

.regimen-section-title {
    font-size: 18px;
    font-weight: 700;
    color: var(--color-primary);
    margin-bottom: var(--spacing-md);
    padding-bottom: var(--spacing-sm);
    border-bottom: 2px solid var(--color-primary);
}

.regimen-card {
    background-color: white;
    border: 2px solid var(--color-border);
    border-radius: var(--border-radius);
    padding: var(--spacing-lg);
    margin-bottom: var(--spacing-md);
    transition: all 0.2s;
}

.regimen-card:hover {
    border-color: var(--color-primary);
    box-shadow: var(--shadow-md);
}

.regimen-card.selected {
    border-color: var(--color-success);
    background-color: #e8f5e9;
    box-shadow: var(--shadow-md);
}

.regimen-header {
    margin-bottom: var(--spacing-md);
    padding-bottom: var(--spacing-md);
    border-bottom: var(--border-width) solid var(--color-border);
}

.regimen-name {
    font-size: 20px;
    font-weight: 700;
    color: var(--color-text);
    margin-bottom: var(--spacing-xs);
}

.regimen-indication {
    display: inline-block;
    padding: var(--spacing-xs) var(--spacing-sm);
    background-color: var(--color-surface);
    border-radius: var(--border-radius);
    font-size: 13px;
    color: var(--color-text-secondary);
}

.regimen-body {
    margin-bottom: var(--spacing-md);
}

.regimen-agents {
    margin-bottom: var(--spacing-md);
}

.agent-item {
    padding: var(--spacing-md);
    margin-bottom: var(--spacing-sm);
    background-color: var(--color-surface);
    border-radius: var(--border-radius);
    border-left: 4px solid var(--color-primary);
}

.agent-name {
    display: block;
    font-size: 16px;
    font-weight: 700;
    color: var(--color-text);
    margin-bottom: var(--spacing-xs);
}

.agent-dose {
    display: inline-block;
    font-size: 15px;
    font-weight: 600;
    color: var(--color-primary);
    margin-right: var(--spacing-sm);
}

.badge-route {
    display: inline-block;
    padding: 2px var(--spacing-sm);
    background-color: var(--color-info);
    color: white;
    border-radius: var(--border-radius);
    font-size: 12px;
    font-weight: 600;
    margin-right: var(--spacing-sm);
}

.agent-monitoring {
    display: block;
    margin-top: var(--spacing-xs);
    font-size: 13px;
    font-weight: 600;
    color: var(--color-warning);
}

.agent-notes {
    display: block;
    margin-top: var(--spacing-xs);
    font-size: 13px;
    color: var(--color-text-secondary);
    font-style: italic;
}

.regimen-footer {
    padding-top: var(--spacing-md);
    border-top: var(--border-width) solid var(--color-border);
}

.regimen-duration {
    display: block;
    font-size: 14px;
    margin-bottom: var(--spacing-sm);
}

.regimen-notes {
    font-size: 13px;
    color: var(--color-text-secondary);
    font-style: italic;
    margin: 0;
}

.regimen-summary-list {
    list-style: none;
    padding: 0;
    margin: var(--spacing-md) 0;
}

.regimen-summary-list li {
    padding: var(--spacing-sm) 0;
    border-bottom: var(--border-width) solid var(--color-surface);
}

/* Phase 4: Dosing Calculations */
.dosing-card {
    background-color: white;
    border: 2px solid var(--color-border);
    border-radius: var(--border-radius);
    padding: var(--spacing-lg);
    margin-bottom: var(--spacing-md);
}

.dosing-card.contraindicated {
    border-color: var(--color-danger);
    background-color: #ffebee;
}

.dosing-header {
    display: flex;
    justify-content: space-between;
    align-items: center;
    margin-bottom: var(--spacing-md);
    padding-bottom: var(--spacing-md);
    border-bottom: var(--border-width) solid var(--color-border);
}

.dosing-header h4 {
    margin: 0;
    font-size: 20px;
    font-weight: 700;
    color: var(--color-text);
}

.dosing-body {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-md);
}

.dose-primary {
    padding: var(--spacing-md);
    background-color: #e3f2fd;
    border-left: 4px solid var(--color-info);
    border-radius: var(--border-radius);
}

.dose-label {
    display: block;
    font-size: 13px;
    font-weight: 600;
    color: var(--color-text-secondary);
    text-transform: uppercase;
    letter-spacing: 0.5px;
    margin-bottom: var(--spacing-xs);
}

.dose-value {
    display: block;
    font-size: 20px;
    font-weight: 700;
    color: var(--color-info);
}

.dose-adjustments {
    padding: var(--spacing-sm);
    background-color: var(--color-surface);
    border-radius: var(--border-radius);
}

.adjustment-label {
    font-size: 13px;
    font-weight: 600;
    color: var(--color-text-secondary);
}

.adjustment-list {
    list-style: disc;
    margin-left: var(--spacing-lg);
    margin-top: var(--spacing-xs);
    margin-bottom: 0;
}

.adjustment-list li {
    font-size: 14px;
    color: var(--color-text);
    margin-bottom: var(--spacing-xs);
}

.dose-notes {
    font-size: 13px;
    color: var(--color-text-secondary);
    font-style: italic;
}

.dose-infusion,
.dose-monitoring {
    font-size: 14px;
    color: var(--color-text);
}

.dose-tdm {
    padding: var(--spacing-sm);
    background-color: #fff3e0;
    border-left: 4px solid var(--color-warning);
    border-radius: var(--border-radius);
    font-size: 14px;
    font-weight: 600;
    color: var(--color-warning);
}

.tdm-requirements {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-lg);
}

.tdm-item {
    padding: var(--spacing-md);
    background-color: var(--color-surface);
    border-left: 4px solid var(--color-warning);
    border-radius: var(--border-radius);
}

.tdm-item h5 {
    margin: 0 0 var(--spacing-sm) 0;
    font-size: 18px;
    font-weight: 700;
    color: var(--color-text);
}

.tdm-timing {
    margin-top: var(--spacing-sm);
    font-size: 13px;
    color: var(--color-text-secondary);
}

.contraindication-list {
    list-style: none;
    padding: 0;
    margin: var(--spacing-md) 0;
}

.contraindication-list li {
    padding: var(--spacing-sm);
    margin-bottom: var(--spacing-sm);
    background-color: #ffcdd2;
    border-left: 4px solid var(--color-danger);
    border-radius: var(--border-radius);
    font-weight: 600;
}

/* Phase 5: Culture State Machine */
.state-diagram {
    display: flex;
    align-items: center;
    justify-content: center;
    flex-wrap: wrap;
    gap: var(--spacing-md);
    padding: var(--spacing-xl);
    background-color: var(--color-surface);
    border-radius: var(--border-radius);
    margin-bottom: var(--spacing-xl);
}

.state-node {
    background-color: white;
    border: 3px solid var(--color-border);
    border-radius: var(--border-radius);
    padding: var(--spacing-md);
    min-width: 150px;
    text-align: center;
    transition: all 0.3s;
    cursor: pointer;
}

.state-node:hover {
    border-color: var(--color-primary);
    box-shadow: var(--shadow-md);
}

.state-node.active {
    border-color: var(--color-success);
    background-color: #e8f5e9;
    box-shadow: var(--shadow-lg);
}

.state-node.state-failure {
    border-color: var(--color-danger);
}

.state-node.state-failure.active {
    background-color: #ffebee;
    border-color: var(--color-danger);
}

.state-number {
    display: inline-block;
    background-color: var(--color-primary);
    color: white;
    padding: var(--spacing-xs) var(--spacing-sm);
    border-radius: 50%;
    font-size: 12px;
    font-weight: 700;
    min-width: 30px;
    margin-bottom: var(--spacing-xs);
}

.state-node.active .state-number {
    background-color: var(--color-success);
}

.state-node.state-failure .state-number {
    background-color: var(--color-danger);
}

.state-name {
    font-size: 14px;
    font-weight: 700;
    color: var(--color-text);
    margin-bottom: var(--spacing-xs);
}

.state-desc {
    font-size: 12px;
    color: var(--color-text-secondary);
}

.state-arrow {
    font-size: 24px;
    color: var(--color-text-secondary);
    font-weight: 700;
}

.state-arrow-branch {
    width: 100%;
    text-align: center;
    font-size: 24px;
    color: var(--color-danger);
    font-weight: 700;
}

.state-guidance {
    background-color: var(--color-surface);
    padding: var(--spacing-lg);
    border-radius: var(--border-radius);
    margin-bottom: var(--spacing-md);
}

.guidance-list {
    list-style: none;
    padding: 0;
    margin: var(--spacing-md) 0;
}

.guidance-list li {
    padding: var(--spacing-sm);
    margin-bottom: var(--spacing-sm);
    background-color: white;
    border-left: 4px solid var(--color-info);
    border-radius: var(--border-radius);
}

.timeline-item {
    padding: var(--spacing-md);
    margin-bottom: var(--spacing-md);
    background-color: white;
    border-left: 4px solid var(--color-primary);
    border-radius: var(--border-radius);
}

.timeline-item strong {
    color: var(--color-primary);
    display: block;
    margin-bottom: var(--spacing-xs);
}

.decision-path {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-md);
    margin-top: var(--spacing-md);
}

.decision-option {
    padding: var(--spacing-md);
    background-color: white;
    border: 2px solid var(--color-border);
    border-radius: var(--border-radius);
    display: flex;
    align-items: flex-start;
    gap: var(--spacing-sm);
    cursor: pointer;
    transition: all 0.2s;
}

.decision-option:hover {
    border-color: var(--color-primary);
    background-color: #e3f2fd;
}

.decision-option input[type="radio"] {
    margin-top: 4px;
}

.organism-checkboxes {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-sm);
}

.organism-checkboxes h5 {
    margin: var(--spacing-md) 0 var(--spacing-sm) 0;
    font-size: 16px;
    font-weight: 700;
    color: var(--color-primary);
    border-bottom: 2px solid var(--color-primary);
    padding-bottom: var(--spacing-xs);
}

.deescalation-recommendation {
    padding: var(--spacing-lg);
    background-color: var(--color-surface);
    border-radius: var(--border-radius);
}

.deescalation-reason {
    padding: var(--spacing-md);
    background-color: #e3f2fd;
    border-left: 4px solid var(--color-info);
    border-radius: var(--border-radius);
    margin-top: var(--spacing-md);
}

.stop-list {
    list-style: none;
    padding: 0;
    margin: var(--spacing-sm) 0;
}

.stop-list li {
    padding: var(--spacing-sm);
    margin-bottom: var(--spacing-xs);
    background-color: white;
    border-left: 4px solid var(--color-danger);
    border-radius: var(--border-radius);
    font-weight: 600;
}

.badge-danger {
    display: inline-block;
    background-color: var(--color-danger);
    color: white;
    padding: 2px var(--spacing-sm);
    border-radius: var(--border-radius);
    font-size: 12px;
    font-weight: 700;
    margin-left: var(--spacing-sm);
}

/* Phase 6: Failure Analysis */
.failure-types {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-md);
}

.failure-type-card {
    background-color: white;
    border: 2px solid var(--color-border);
    border-radius: var(--border-radius);
    padding: var(--spacing-lg);
    cursor: pointer;
    transition: all 0.2s;
    display: flex;
    gap: var(--spacing-md);
}

.failure-type-card:hover {
    border-color: var(--color-primary);
    box-shadow: var(--shadow-md);
}

.failure-type-card.selected {
    border-color: var(--color-success);
    background-color: #e8f5e9;
}

.failure-type-header {
    font-size: 16px;
    font-weight: 700;
    color: var(--color-text);
    margin-bottom: var(--spacing-xs);
}

.failure-type-desc {
    font-size: 14px;
    color: var(--color-text-secondary);
}

.override-tiers {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-md);
}

.override-tier {
    padding: var(--spacing-md);
    background-color: var(--color-surface);
    border-left: 4px solid var(--color-primary);
    border-radius: var(--border-radius);
}

.override-tier h4 {
    margin: 0 0 var(--spacing-xs) 0;
    color: var(--color-primary);
}

.telemetry-summary {
    background-color: var(--color-surface);
    padding: var(--spacing-lg);
    border-radius: var(--border-radius);
}

.telemetry-list {
    list-style: none;
    padding: 0;
    margin: var(--spacing-md) 0;
}

.telemetry-list li {
    padding: var(--spacing-sm);
    margin-bottom: var(--spacing-xs);
    background-color: white;
    border-radius: var(--border-radius);
}

/* Phase 7: Modifiers */
.modifier-badges {
    display: flex;
    flex-wrap: wrap;
    gap: var(--spacing-sm);
    margin: var(--spacing-md) 0;
}

.modifier-badge {
    display: inline-block;
    padding: var(--spacing-sm) var(--spacing-md);
    background-color: var(--color-info);
    color: white;
    border-radius: var(--border-radius);
    font-size: 14px;
    font-weight: 600;
}

.modifier-checkboxes {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-sm);
}

.modifier-impact-list {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-md);
}

.modifier-impact-item {
    padding: var(--spacing-lg);
    border-left: 4px solid var(--color-info);
    border-radius: var(--border-radius);
    background-color: #e3f2fd;
}

.modifier-impact-item.warning {
    border-left-color: var(--color-warning);
    background-color: #fff3e0;
}

.modifier-impact-item.danger {
    border-left-color: var(--color-danger);
    background-color: #ffebee;
}

.modifier-actions {
    margin-top: var(--spacing-md);
    padding: var(--spacing-md);
    background-color: white;
    border-radius: var(--border-radius);
}

.conflict-resolution {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-lg);
}

.conflict-item {
    padding: var(--spacing-lg);
    border: 2px solid var(--color-danger);
    border-radius: var(--border-radius);
    background-color: #ffebee;
}

.conflict-item h4 {
    margin: 0 0 var(--spacing-md) 0;
    color: var(--color-danger);
}

.final-summary {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-lg);
}

.summary-section {
    padding: var(--spacing-md);
    background-color: var(--color-surface);
    border-radius: var(--border-radius);
}

.summary-section h4 {
    margin: 0 0 var(--spacing-sm) 0;
    font-size: 16px;
    font-weight: 700;
    color: var(--color-primary);
}

.completion-checklist {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-md);
}

.checklist-item {
    display: flex;
    align-items: flex-start;
    gap: var(--spacing-sm);
    padding: var(--spacing-sm);
    background-color: var(--color-surface);
    border-radius: var(--border-radius);
}

.checklist-item input[type="checkbox"] {
    margin-top: 4px;
}

.completion-checkbox[disabled] {
    opacity: 0.6;
}

/* Responsive Adjustments */
@media (max-width: 768px) {
    .state-diagram {
        flex-direction: column;
    }
    
    .state-arrow {
        transform: rotate(90deg);
    }
    
    .syndrome-grid {
        grid-template-columns: 1fr;
    }
    
    .patient-data-grid {
        grid-template-columns: 1fr;
    }
    
    .form-row {
        grid-template-columns: 1fr;
    }
    
    .data-review-grid {
        grid-template-columns: 1fr;
    }
    
    .phase-navigation {
        flex-direction: column;
        gap: var(--spacing-sm);
    }
    
    .phase-navigation .btn {
        width: 100%;
    }
    
    /* Save & Pause button first on mobile for visibility */
    .phase-navigation .btn-warning,
    #pause-case-phase3,
    #pause-case-phase4,
    #pause-case-phase5,
    #pause-case-phase6,
    #pause-case-phase7 {
        order: 1;
        background-color: #ff9800 !important;
        font-size: 16px;
    }
    
    .phase-navigation .btn-primary {
        order: 2;
    }
    
    .phase-navigation .btn-secondary {
        order: 3;
    }
    
    /* FIX #5: Prevent footer overlap - add bottom spacing */
    .phase-navigation,
    .phase-actions,
    #phase-navigation-buttons {
        margin-bottom: 60px !important;
        padding-bottom: var(--spacing-lg);
    }
}

/* Biological Validation Styling (P3a) */
.disabled-field {
    opacity: 0.5;
    pointer-events: none;
    position: relative;
}

.disabled-field::after {
    content: '🔒';
    position: absolute;
    right: 8px;
    top: 50%;
    transform: translateY(-50%);
    font-size: 14px;
    opacity: 0.6;
}

.disabled-field input[type="checkbox"] {
    cursor: not-allowed;
}

.disabled-field label {
    cursor: not-allowed;
    color: var(--color-text-secondary);
}

.biological-notification {
    position: fixed;
    top: 100px;
    right: 20px;
    background-color: #e3f2fd;
    color: var(--color-info);
    padding: var(--spacing-md) var(--spacing-lg);
    border-radius: var(--border-radius);
    border-left: 4px solid var(--color-info);
    box-shadow: var(--shadow-md);
    font-size: 14px;
    font-weight: 600;
    z-index: 9999;
    max-width: 400px;
    animation: slideIn 0.3s ease;
    transition: opacity 0.3s;
}

@keyframes slideIn {
    from {
        transform: translateX(100%);
        opacity: 0;
    }
    to {
        transform: translateX(0);
        opacity: 1;
    }
}

/* Allergy System Styling (P3b) */
.allergy-system {
    background-color: white;
    padding: var(--spacing-lg);
    border-radius: var(--border-radius);
    border: 2px solid #FFA726;
    margin-bottom: var(--spacing-lg);
}

.allergy-system h3 {
    margin: 0 0 var(--spacing-sm) 0;
    color: var(--color-text);
}

.allergy-classes {
    display: grid;
    grid-template-columns: 1fr;
    gap: var(--spacing-md);
}

.allergy-class-item {
    padding: var(--spacing-md);
    background-color: var(--color-surface);
    border-radius: var(--border-radius);
    border: 1px solid var(--color-border);
}

.allergy-checkbox-group {
    display: flex;
    align-items: center;
    gap: var(--spacing-sm);
}

.allergy-checkbox-group label {
    font-weight: 600;
    color: var(--color-text);
    cursor: pointer;
}

.allergy-agents {
    display: block;
    font-size: 13px;
    color: var(--color-text-secondary);
    font-weight: 400;
    margin-top: 2px;
}

.allergy-severity-group {
    margin-top: var(--spacing-md);
    padding: var(--spacing-md);
    background-color: white;
    border-radius: var(--border-radius);
    border-left: 4px solid #FFA726;
}

.severity-label,
.notes-label {
    display: block;
    font-weight: 600;
    margin-bottom: var(--spacing-xs);
    font-size: 14px;
}

.allergy-severity-select {
    width: 100%;
    padding: var(--spacing-sm);
    border: 2px solid var(--color-border);
    border-radius: 4px;
    font-size: 15px;
    margin-bottom: var(--spacing-md);
}

.allergy-notes-group {
    margin-top: var(--spacing-md);
}

.allergy-notes-input {
    width: 100%;
    padding: var(--spacing-sm);
    border: 2px solid var(--color-border);
    border-radius: 4px;
    font-size: 14px;
}

.allergy-summary {
    margin-top: var(--spacing-lg);
    padding: var(--spacing-md);
    background-color: #FFF3E0;
    border-radius: var(--border-radius);
    border: 2px solid #FFA726;
}

.allergy-summary h4 {
    margin: 0 0 var(--spacing-md) 0;
    color: var(--color-text);
}

.allergy-summary-item {
    padding: var(--spacing-sm) var(--spacing-md);
    background-color: white;
    border-radius: 4px;
    border-left: 4px solid #FFA726;
    margin-bottom: var(--spacing-sm);
}

.allergy-summary-item:last-child {
    margin-bottom: 0;
}

.allergy-summary-class {
    font-weight: 700;
    font-size: 15px;
    color: var(--color-text);
}

.allergy-summary-severity {
    font-weight: 600;
    font-size: 14px;
    margin-top: 2px;
}

.allergy-summary-notes {
    font-size: 13px;
    color: var(--color-text-secondary);
    margin-top: 4px;
    font-style: italic;
}

.allergy-block-message {
    padding: var(--spacing-md);
    background-color: #FFEBEE;
    border-left: 4px solid var(--color-danger);
    border-radius: var(--border-radius);
    margin: var(--spacing-md) 0;
}

.allergy-block-message h4 {
    margin: 0 0 var(--spacing-sm) 0;
}

.allergy-block-message p {
    margin: var(--spacing-xs) 0;
}

.allergy-block-action {
    font-weight: 600;
    margin-top: var(--spacing-md);
}

@media (max-width: 768px) {
    .allergy-system {
        padding: var(--spacing-md);
    }
    
    .allergy-classes {
        gap: var(--spacing-sm);
    }
}

/* Resistance Display System (P4) */
.organism-card {
    background-color: white;
    border: 2px solid var(--color-border);
    border-radius: var(--border-radius);
    padding: var(--spacing-md);
    margin-bottom: var(--spacing-md);
    box-shadow: var(--shadow-sm);
}

.organism-header {
    margin-bottom: var(--spacing-md);
}

.organism-name-row {
    display: flex;
    align-items: center;
    gap: var(--spacing-sm);
    margin-bottom: var(--spacing-sm);
}

.organism-category-badge {
    width: 32px;
    height: 32px;
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    font-size: 18px;
}

.organism-name {
    margin: 0;
    font-size: 18px;
    font-weight: 700;
    color: var(--color-text);
}

.resistance-badges {
    display: flex;
    gap: var(--spacing-xs);
    flex-wrap: wrap;
}

.resistance-badge {
    display: inline-flex;
    align-items: center;
    gap: 4px;
    padding: 4px var(--spacing-sm);
    border-radius: 12px;
    font-size: 12px;
    font-weight: 700;
    color: white;
    text-transform: uppercase;
    letter-spacing: 0.5px;
}

.organism-details {
    margin-top: var(--spacing-md);
    padding-top: var(--spacing-md);
    border-top: 1px solid var(--color-border);
}

.organism-detail {
    font-size: 14px;
    color: var(--color-text);
    margin-bottom: var(--spacing-xs);
}

.organism-detail strong {
    font-weight: 600;
    color: var(--color-text-secondary);
}

.resistance-implications {
    margin-top: var(--spacing-md);
    padding: var(--spacing-md);
    background-color: #FFF3E0;
    border-radius: var(--border-radius);
    border-left: 4px solid #FF9800;
}

.resistance-implications h5 {
    margin: 0 0 var(--spacing-xs) 0;
    font-size: 14px;
    font-weight: 700;
    color: var(--color-text);
}

.resistance-implication {
    margin: var(--spacing-xs) 0;
    font-size: 13px;
    color: var(--color-text);
    line-height: 1.5;
}

.blocking-explanation {
    display: flex;
    gap: var(--spacing-md);
    padding: var(--spacing-md);
    border-radius: var(--border-radius);
    margin: var(--spacing-md) 0;
    border-left: 4px solid;
}

.blocking-explanation.susceptible {
    background-color: #E8F5E9;
    border-color: #4CAF50;
}

.blocking-explanation.resistant {
    background-color: #FFEBEE;
    border-color: #F44336;
}

.blocking-explanation.resistance-pattern {
    background-color: #FFF3E0;
    border-color: #FF9800;
}

.explanation-icon {
    font-size: 24px;
    flex-shrink: 0;
}

.explanation-content {
    font-size: 14px;
    line-height: 1.6;
}

.explanation-content strong {
    display: block;
    margin-bottom: 4px;
    color: var(--color-text);
}

.drug-status-indicator {
    padding: var(--spacing-sm);
    border-radius: var(--border-radius);
    border: 2px solid;
    margin-bottom: var(--spacing-sm);
}

.drug-status-header {
    display: flex;
    align-items: center;
    gap: var(--spacing-xs);
    margin-bottom: 4px;
}

.drug-status-icon {
    font-size: 18px;
}

.drug-status-label {
    font-weight: 700;
    font-size: 13px;
    text-transform: uppercase;
    letter-spacing: 0.5px;
}

.drug-status-drug {
    font-weight: 600;
    font-size: 15px;
    color: var(--color-text);
    margin-bottom: 4px;
}

.drug-status-reason {
    font-size: 13px;
    color: var(--color-text-secondary);
    font-style: italic;
}

.compatibility-matrix {
    margin: var(--spacing-lg) 0;
}

.compatibility-matrix h4 {
    margin: 0 0 var(--spacing-md) 0;
    font-size: 16px;
    color: var(--color-text);
}

.compatibility-grid {
    display: grid;
    grid-template-columns: repeat(auto-fill, minmax(250px, 1fr));
    gap: var(--spacing-md);
}

.resistance-summary {
    display: flex;
    align-items: center;
    gap: var(--spacing-md);
    padding: var(--spacing-md);
    border-radius: var(--border-radius);
    margin-bottom: var(--spacing-lg);
}

.resistance-summary.success {
    background-color: #E8F5E9;
    border: 2px solid #4CAF50;
}

.resistance-summary.warning {
    background-color: #FFF3E0;
    border: 2px solid #FF9800;
}

.summary-icon {
    font-size: 24px;
}

.summary-text {
    font-size: 15px;
    font-weight: 600;
    color: var(--color-text);
}

.no-organisms {
    padding: var(--spacing-lg);
    text-align: center;
    color: var(--color-text-secondary);
    font-style: italic;
}

@media (max-width: 768px) {
    .organism-card {
        padding: var(--spacing-sm);
    }
    
    .compatibility-grid {
        grid-template-columns: 1fr;
    }
    
    .resistance-badges {
        flex-direction: column;
    }
    
    .blocking-explanation {
        flex-direction: column;
        gap: var(--spacing-sm);
    }
}

/* P7 Governance: Locked State Styling */
.status-locked {
    display: inline-block;
    padding: 4px 12px;
    background-color: #FFF3E0;
    color: #E65100;
    border-radius: 4px;
    font-weight: 700;
    font-size: 13px;
}

.metadata-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: var(--spacing-md);
    margin-top: var(--spacing-md);
}

.metadata-grid div {
    padding: var(--spacing-sm);
    background-color: var(--color-surface);
    border-radius: 4px;
    font-size: 14px;
}

.metadata-grid strong {
    color: var(--color-text-secondary);
    font-weight: 600;
}

/* LEVEL B: Pharmacy Review UI Styling */
.checkbox-label {
    display: flex;
    align-items: center;
    gap: 10px;
    cursor: pointer;
    font-size: 16px;
    font-weight: 600;
    padding: 12px;
    background-color: #f8f9fa;
    border-radius: 4px;
    transition: background-color 0.2s;
}

.checkbox-label:hover {
    background-color: #e9ecef;
}

.form-checkbox {
    width: 20px;
    height: 20px;
    cursor: pointer;
}

.form-checkbox:checked + span {
    color: var(--color-success);
}

.qtc-risk-list {
    margin: 10px 0;
    padding-left: 20px;
}

.qtc-risk-list li {
    margin: 5px 0;
    font-size: 14px;
}